Age-dependent effects of SGLT2 inhibitors on stroke risk in geriatric patients with diabetes and atrial fibrillation
The impact of SGLT2i on stroke risk varies significantly by age. While protective in younger patients, SGLT2i may increase stroke risk in those aged ≥ 90 years. These findings highlight the importance of age-specific considerations in prescribing SGLT2i for patients with AF and DM.
Authors
- Fu‐Chun Chiu (ORCID: https://orcid.org/0000-0002-8282-485X)
- Su-Kiat Chua
- Sheng‐Nan Chang (ORCID: https://orcid.org/0000-0002-2663-5042)
- Juey-Jen Hwang
- Jien‐Jiun Chen (ORCID: https://orcid.org/0000-0002-1848-6083)
- Yi‐Chih Wang (ORCID: https://orcid.org/0000-0003-2533-865X)
- Chih-Hsien Wang
- Pang‐Shuo Huang (ORCID: https://orcid.org/0000-0002-8210-2486)
- Chia-Ti Tsai
Institutions
- Fu Jen Catholic University (TW)
- National Taiwan University Hospital (TW)
- National Yunlin University of Science and Technology (TW)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12933-024-02557-9
- Citations
- 3
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.88
Funders
- National Science and Technology Council