Simultaneous Activation of Beta‐Oxidation and De Novo Lipogenesis in <scp>MASLD</scp>‐<scp>HCC</scp>: A New Paradigm
These results suggest that, the involvement of adaptive metabolic pathways is different depending on the aetiology of HCC. Moreover, the dogma that simultaneous activation of FAO and DNL is incompatible in cancer would not apply to MASLD-HCC.
Authors
- Adrien Rossary (ORCID: https://orcid.org/0000-0001-8311-2419)
- Natali Abeywickrama Samarakoon (ORCID: https://orcid.org/0000-0002-2451-604X)
- Delphine Weil (ORCID: https://orcid.org/0000-0002-9648-813X)
- Vincent Di Martino (ORCID: https://orcid.org/0000-0002-2022-690X)
- Jihan Sun (ORCID: https://orcid.org/0000-0002-3811-6434)
- Fatima Dahboul
- Armand Abergel (ORCID: https://orcid.org/0000-0001-7480-1052)
- Stéphanie Durand (ORCID: https://orcid.org/0000-0003-2434-9429)
- Massimo Levrero (ORCID: https://orcid.org/0000-0002-4978-0875)
- Massimiliano Cocca (ORCID: https://orcid.org/0000-0002-1127-7596)
- Mélanie Pétéra (ORCID: https://orcid.org/0000-0002-1779-6901)
- Estelle Pujos‐Guillot (ORCID: https://orcid.org/0000-0002-4693-5712)
- Aïcha Demidem (ORCID: https://orcid.org/0000-0003-2153-344X)
- Benjamin Buchard (ORCID: https://orcid.org/0000-0002-9347-7638)
- Delphine Centeno (ORCID: https://orcid.org/0000-0002-2747-6290)
- F. Guerrieri (ORCID: https://orcid.org/0000-0003-2751-6050)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Clermont Auvergne (FR)
- Unité de Nutrition Humaine (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Institut d'Asie Orientale (FR)
- Hospices Civils de Lyon (FR)
- University of Clermont Auvergne (FR)
- Centre de Recherche en Cancérologie de Lyon (FR)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- Centre de Recherche en Nutrition Humaine d'Auvergne (FR)
Publication Details
- Journal
- Liver International
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1111/liv.70006
- Citations
- 8
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.83
Funders
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Société Nationale Française de Gastro-Entérologie
- Emergence de Jeune Equipe INRA
- Université Clermont-Auvergne