Genchain: A Blockchain Based Genetic Disease Prediction System

Genetic testing can be used to learn about the genetic disorders a person may have based on their family history; however, they are overpriced and out of reach for many. We propose Genchain, which is a secure, private consortium blockchain system that calculates the probability of genetic diseases. Our system stores the information of the genetic diseases a user and their family have in a blockchain, and when requested, calculates the possible genetic disease percentages. The solution involves sending genetic disease data from all hospitals registered in the private system to Genchain, along with the family numbers of the patients taken from a trusted authority. Genchain uses the Paillier cryptosystem, a probabilistic asymmetric method for public key cryptography, which has the property of homomorphism, which we will use in our encryption scheme to protect the confidentiality and privacy of the system.

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Publication Details

Published
2024-11-26
DOI
https://doi.org/10.1109/bcca62388.2024.10844437
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
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article

Genchain: A Blockchain Based Genetic Disease Prediction System

Kübra Kalkan, Muhammed Esad Simitcioğlu
Bioinformatics and Genomic Networks
article

Genchain: A Blockchain Based Genetic Disease Prediction System

Kübra Kalkan, Muhammed Esad Simitcioğlu
article en

Abstract

Genetic testing can be used to learn about the genetic disorders a person may have based on their family history; however, they are overpriced and out of reach for many. We propose Genchain, which is a secure, private consortium blockchain system that calculates the probability of genetic diseases. Our system stores the information of the genetic diseases a user and their family have in a blockchain, and when requested, calculates the possible genetic disease percentages. The solution involves sending genetic disease data from all hospitals registered in the private system to Genchain, along with the family numbers of the patients taken from a trusted authority. Genchain uses the Paillier cryptosystem, a probabilistic asymmetric method for public key cryptography, which has the property of homomorphism, which we will use in our encryption scheme to protect the confidentiality and privacy of the system.

Openalex Percentile: Top 78%
Bioinformatics and Genomic Networks
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