Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis
Our multi-omics analysis provides preliminary evidence for potential molecular mechanisms in psoriasis pathogenesis. Through the integration of GWAS and molecular QTL data, we identify candidate pathways that may be relevant to disease biology. While these findings require extensive experimental validation, they offer a framework for future investigations into the molecular basis of psoriasis.
Authors
- Jinyang Gao (ORCID: https://orcid.org/0000-0001-8247-1196)
- Yanqing Wang (ORCID: https://orcid.org/0000-0002-8072-8899)
- Liping Gong
- Hua Guo (ORCID: https://orcid.org/0000-0001-5433-0759)
Institutions
- Allen Institute for Brain Science (US)
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12967-025-06099-w
- Citations
- 5
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 3.99
Funders
- Natural Science Foundation for Young Scientists of Shanxi Province