True cancer stem cells exhibit relative degrees of dormancy and genomic stability
These studies indicate that a truly biological cancer stem cell subpopulation exists that exhibits both dormancy and genomic stability. This subpopulation could not have been derived from the proliferating and resulting genomically unstable population and therefore represents a truly hierarchical stem cell subpopulation capable of only unidirectional differentiation.
Authors
- Sanford H. Barsky (ORCID: https://orcid.org/0000-0002-3760-4989)
- Clayton W. Beard
- Kerry L. McPhail (ORCID: https://orcid.org/0000-0003-2076-1002)
- Justin Wang (ORCID: https://orcid.org/0000-0003-4734-4524)
- Yin Ye
- Jordan Dillard
Institutions
- Meharry Medical College (US)
- University of Nevada, Las Vegas (US)
- Scripps Mercy Hospital (US)
Publication Details
- Journal
- Neoplasia
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1016/j.neo.2025.101127
- Citations
- 1
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Institutes of Health
- Medical Research and Materiel Command