Silent In-Stent Thrombosis Diagnosed by Optical Coherence Tomography and Histopathology of Directional Coronary Atherectomy Specimen
A 75-year-old woman who underwent percutaneous coronary intervention using an everolimus-eluting stent showed silent in-stent occlusion. Pathological examination of the neointima, resected through directional coronary atherectomy, revealed a double-layered neointima with neointimal hyperplasia and thrombus. Stent-edge restenosis and subsequent thrombosis, related to clopidogrel resistance, likely caused the in-stent thrombotic occlusion.
Authors
- Yusuke Shirai (ORCID: https://orcid.org/0000-0003-4146-3901)
- Atsushi Sakamoto (ORCID: https://orcid.org/0000-0002-6372-9224)
- Hayato Ohtani
- Yuichiro Maekawa (ORCID: https://orcid.org/0000-0002-6792-8458)
- Masahiro Muto (ORCID: https://orcid.org/0000-0001-8623-5940)
- Shinya Fujita
Institutions
- Hamamatsu University (JP)
- Hamamatsu University School of Medicine (JP)
- Hamamatsu Medical Center (JP)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1016/j.jaccas.2024.102971
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science