Pretargeted Trop-2 ImmunoPET for Rapid, Selective Detection of Pancreatic Tumors

[89Zr]Zr-deferoxamine-Trop-2 and pretargeting with [64Cu]Cu-sarcophagine-tetrazine are viable imaging strategies to quickly identify Trop-2-positive tumors for subsequent Trop-2 therapies. See related commentary by Mori et al., p. 2547.

Authors

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Publication Details

Journal
Clinical Cancer Research
Published
2025-01-22
DOI
https://doi.org/10.1158/1078-0432.ccr-24-3098
Citations
9
Primary Topic
Advanced biosensing and bioanalysis techniques
Type
article
Field-Weighted Citation Impact
7.25

Funders

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article

Pretargeted Trop-2 ImmunoPET for Rapid, Selective Detection of Pancreatic Tumors

David Bauer, Alexander Bolaender, Edwin C. Pratt, Jason S. Lewis et al.
9 citations
Clinical Cancer Research
Advanced biosensing and bioanalysis techniques
7.25
article

Pretargeted Trop-2 ImmunoPET for Rapid, Selective Detection of Pancreatic Tumors

David Bauer, Alexander Bolaender, Edwin C. Pratt, Jason S. Lewis, Grace Chao, Mark Castanares, Komal Mandleywala, Emily C. Collins
article en
9 citations

Abstract

[89Zr]Zr-deferoxamine-Trop-2 and pretargeting with [64Cu]Cu-sarcophagine-tetrazine are viable imaging strategies to quickly identify Trop-2-positive tumors for subsequent Trop-2 therapies. See related commentary by Mori et al., p. 2547.

Clinical Cancer ResearchVol. 31(13)
Memorial Sloan Kettering Cancer Center (US), Eli Lilly (United States) (US), Cornell University (US), University of Missouri (US)
National Institutes of Health
Good health and well-being
Openalex Percentile: Top 3%
Advanced biosensing and bioanalysis techniques
7.25
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