Biological One-way Functions

Biology has been a rich source of inspiration for computer security professionals.The central dogma of biology contains intronization cipher and substitution cipher with three many-to-one mappings.In cryptography, substitution cipher has been used long before human identifies DNA.However, it seems that no enough attention has been paid to the intronization cipher because it alone does not make a good cipher.In this paper, the intronization cipher with pseudo-random sequence and substitution cipher with modified genetic code are proposed to improve the security of the intronization cipher.Inverse mapping from protein to RNA and from ciphertext to plaintext are extremely hard; therefore we prefer to treat these ciphers as two biological one-way functions.

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Publication Details

Published
2025-01-22
DOI
https://doi.org/10.18260/1-2-1153-50172
Primary Topic
Origins and Evolution of Life
Type
article
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article

Biological One-way Functions

Michael Anshel, Xiaowen Zhang, Qinghai Gao
Origins and Evolution of Life
article

Biological One-way Functions

Michael Anshel, Xiaowen Zhang, Qinghai Gao
article en

Abstract

Biology has been a rich source of inspiration for computer security professionals.The central dogma of biology contains intronization cipher and substitution cipher with three many-to-one mappings.In cryptography, substitution cipher has been used long before human identifies DNA.However, it seems that no enough attention has been paid to the intronization cipher because it alone does not make a good cipher.In this paper, the intronization cipher with pseudo-random sequence and substitution cipher with modified genetic code are proposed to improve the security of the intronization cipher.Inverse mapping from protein to RNA and from ciphertext to plaintext are extremely hard; therefore we prefer to treat these ciphers as two biological one-way functions.

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Origins and Evolution of Life
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Biological One-way Functions — Michael Anshel, Xiaowen Zhang, et al. · (2025) | TGRS Research Map | TGRS