Clinical efficacy of 0.1% cyclosporine A in dry eye patients with inadequate responses to 0.05% cyclosporine A: a switching, prospective, open-label, multicenter study
In patients with dry eye disease (DED) who exhibited inadequate responses to 0.05% cyclosporine A (CsA), switching to 0.1% CsA resulted in significant improvements in both subjective symptoms and objective clinical signs. This finding suggests that higher concentrations of CsA may be more effective in treating individuals with moderate to severe DED.
Authors
- In Cheon You (ORCID: https://orcid.org/0000-0002-3480-5857)
- Joon Young Hyon (ORCID: https://orcid.org/0000-0003-3620-1536)
- Jong Suk Song (ORCID: https://orcid.org/0000-0002-7187-8094)
- Chul Young Choi (ORCID: https://orcid.org/0000-0002-3453-3505)
- Kyoung Yul Seo (ORCID: https://orcid.org/0000-0002-9855-1980)
- Eun Chul Kim (ORCID: https://orcid.org/0000-0002-0310-5663)
- Hong Kyun Kim (ORCID: https://orcid.org/0000-0002-9283-3506)
- Jae Yong Kim (ORCID: https://orcid.org/0000-0001-8571-8350)
- Sook Hyun Yoon (ORCID: https://orcid.org/0009-0000-5877-6555)
Institutions
- Ulsan College (KR)
- Yonsei University (KR)
- Korea University (KR)
- Asan Medical Center (KR)
- Seoul National University Bundang Hospital (KR)
- Kyungpook National University (KR)
- Daegu Catholic University (KR)
- University of Ulsan (KR)
- Kangbuk Samsung Hospital (KR)
- The Catholic University of Korea Bucheon St. Mary's Hospital (KR)
- Yonsei University Health System (KR)
- Jeonbuk National University (KR)
- Sungkyunkwan University (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- BMC Ophthalmology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12886-025-03862-x
- Citations
- 1
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Santen