The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome
This study demonstrates significantly altered levels of 1-deoxySL and polyamines, with corresponding enzyme activity changes, in placental syndrome compared to healthy pregnancies. The disrupted correlations between these biomolecules suggest alterations in their metabolic pathways and potential utility as biomarkers. Further mechanistic studies are warranted to elucidate their role in placental syndrome pathophysiology.
Authors
- Göknil Pelin Coşkun (ORCID: https://orcid.org/0000-0001-5168-3866)
- Filiz Yarşılıkal Güleroğlu (ORCID: https://orcid.org/0000-0003-4577-3368)
- Ali Çetin (ORCID: https://orcid.org/0000-0002-5767-7894)
- Sinem Tekin (ORCID: https://orcid.org/0000-0003-4183-6472)
- Çilem Bilginer (ORCID: https://orcid.org/0000-0003-3375-3183)
- Yusuf Tutar (ORCID: https://orcid.org/0000-0003-2613-9644)
- Tugce Caklili
- Meltem Caliskan
- Fulya Karaduman
- Resat Misirlioglu (ORCID: https://orcid.org/0009-0002-7221-0042)
- Merve Nur Al
Institutions
- Recep Tayyip Erdoğan University (TR)
- Haseki Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Kent Hastanesi (TR)
- Acıbadem Adana Hospital (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12884-025-07175-1
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- Türkiye Sağlık Enstitüleri Başkanlığı