Epigenome-wide association study of Chinese monozygotic twins identifies DNA methylation loci associated with estimated glomerular filtration rate
We identified a set of CpGs, DMRs, and pathways potentially associated with eGFR, particularly in the SYNGR3 gene. These findings provided new insights into the epigenetic modifications related to the decline in eGFR and chronic kidney disease.
Authors
- Xueting Qi
- Tong Wang (ORCID: https://orcid.org/0000-0002-9403-7167)
- Dongfeng Zhang (ORCID: https://orcid.org/0000-0001-9308-9371)
- Weijing Wang (ORCID: https://orcid.org/0000-0001-7747-7649)
- Jingjing Wang (ORCID: https://orcid.org/0009-0001-5376-8836)
Institutions
- Qingdao University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12967-025-06067-4
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China