The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load
This study provides a comprehensive and precise genomic analysis and interpretation of Tibetan sheep, offering theoretical basis for genetic breeding and evolution in Tibetan sheep.
Authors
- Zengkui Lu (ORCID: https://orcid.org/0000-0002-5993-1083)
- Chao Yuan (ORCID: https://orcid.org/0000-0003-1403-7675)
- Tingting Guo (ORCID: https://orcid.org/0000-0003-1360-3807)
- Lixia Sun (ORCID: https://orcid.org/0000-0001-6380-3853)
- Jianbin Liu
- Yaqin Bai
Institutions
- Lanzhou Institute of Husbandry and Pharmaceutical Sciences (CN)
- Chinese Academy of Agricultural Sciences (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12864-025-11207-7
- Primary Topic
- Genetic and phenotypic traits in livestock
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Agricultural Sciences
- Agricultural Science and Technology Innovation Program
- Science and Technology Program of Gansu Province