Intravesical Instillation of Chemotherapy Before Radical Surgery for Upper Urinary Tract Urothelial Carcinoma: The REBACARE Trial

Preoperative IIC with mitomycin C was feasible and well tolerated and significantly reduced IVR risk for patients without d-URS. These findings suggest that preoperative IIC is a viable strategy for this subset of UTUC patients and that d-URS should be performed judiciously.

Authors

Institutions

Publication Details

Journal
European Urology
Published
2025-01-22
DOI
https://doi.org/10.1016/j.eururo.2024.12.006
Citations
16
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
32.10

Funders

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article

Intravesical Instillation of Chemotherapy Before Radical Surgery for Upper Urinary Tract Urothelial Carcinoma: The REBACARE Trial

Katja K.H. Aben, Jorg R. Oddens, Peter de Vries, Erik B. Cornel et al.
16 citations
European Urology
Bladder and Urothelial Cancer Treatments
32.10
article

Intravesical Instillation of Chemotherapy Before Radical Surgery for Upper Urinary Tract Urothelial Carcinoma: The REBACARE Trial

Katja K.H. Aben, Jorg R. Oddens, Peter de Vries, Erik B. Cornel, Sebastiaan Remmers, L.A.J. Roelofs, Bob Merks, Benjamin Pradère, Richard P. Meijer, Diederik M. Somford, Antoine G. van der Heijden, Bin K. Kroon, Peter J. Zwaan, Harm van Melick, Thomas van Doeveren, Anna M. Leliveld, Marit J. Yska, Kees Hendricksen, Joost L. Boormans, Egbert R. Boevé, Pim J. van Leeuwen, Rens A. L. Jacobs, Bart P. Wijsman, Evelyne C. C. Cauberg, Willemijn A.K.M. Windt
article en
16 citations

Abstract

Preoperative IIC with mitomycin C was feasible and well tolerated and significantly reduced IVR risk for patients without d-URS. These findings suggest that preoperative IIC is a viable strategy for this subset of UTUC patients and that d-URS should be performed judiciously.

European UrologyVol. 87(4)
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), Gelre Hospitals (NL), Radboud University Medical Center (NL), The Netherlands Cancer Institute (NL), University Medical Center Utrecht (NL), Sint Franciscus Gasthuis (NL), Medisch Centrum Haaglanden (NL), St. Antonius Ziekenhuis (NL), Amsterdam Neuroscience (NL), Maasstad Ziekenhuis (NL), Treant Zorggroep (NL), Martini Ziekenhuis (NL), Groupe Hospitalier Diaconesses Croix Saint-Simon (FR), Canisius-Wilhelmina Ziekenhuis (NL), Zuyderland Medisch Centrum (NL), Netherlands Comprehensive Cancer Organisation (NL), Isala (NL), Elisabeth-TweeSteden Ziekenhuis (NL), Ziekenhuis Groep Twente (NL), Erasmus MC Cancer Institute (NL), Franciscus Vlietland (NL), Rijnstate Hospital (NL), Amsterdam University of Applied Sciences (NL), University of Amsterdam (NL)
KWF Kankerbestrijding
Good health and well-being
Openalex Percentile: Top 0%
Bladder and Urothelial Cancer Treatments
32.10
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