Apoptosis antagonizing transcription factor expression and its validation as a potential diagnostic and prognostic biomarker in oral squamous cell carcinoma
Elevated expression of AATF in OSCC correlates with adverse clinicopathological features and negatively impacts immune cell infiltration. High AATF levels serve as an independent marker of poor OS and DSS. These findings support AATF as a valuable prognostic biomarker and a potential therapeutic target in OSCC, warranting further investigation.
Authors
- Ainiwaerjiang Abudourousuli
- Chengli Da
- Zumulaiti Aierken
- Hasiyati Mamuti
- Tuxunayi Yimamu
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fonc.2025.1542730
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Xinjiang