Causal associations between osteoporosis and HBV infection across Asian and European populations: evidence from Mendelian randomization and colocalization analysis
Our study identified a causal relationship between HBV infection and osteoporosis in East Asian and European populations. These results provided strong evidence that HBV infection augmented the risk of developing osteoporosis in East Asian populations and provided novel therapeutic targets.
Authors
- Zhendong Tian (ORCID: https://orcid.org/0000-0002-3271-5372)
- Rui Cao (ORCID: https://orcid.org/0000-0001-7757-7615)
- Zhongjun Cheng (ORCID: https://orcid.org/0000-0001-5550-2989)
- Zhengnan Li (ORCID: https://orcid.org/0000-0003-3268-2096)
- Yiyang Han (ORCID: https://orcid.org/0009-0005-1616-4346)
- Bangqi Wang (ORCID: https://orcid.org/0000-0002-2142-1969)
- Zimian Luo (ORCID: https://orcid.org/0000-0003-2946-7686)
- Yuping Lai (ORCID: https://orcid.org/0000-0001-7445-6738)
- Chen Shen (ORCID: https://orcid.org/0009-0006-9371-8063)
- Yixin Wu (ORCID: https://orcid.org/0000-0002-3000-9423)
- Jiarui Cao (ORCID: https://orcid.org/0009-0005-4073-0344)
- Ke Li (ORCID: https://orcid.org/0009-0007-3113-4115)
Institutions
- Nanchang University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Ganzhou People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fendo.2024.1419303
- Citations
- 2
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71