Separation Surgery Followed by Conformal Postoperative Spine Stereotactic Body Radiation Therapy Does Not Increase Risk of Adjacent Spine Level Progression in the Management of Spine Metastases
Spine oncology patients treated with surgery followed by conformal postoperative S-SBRT had similar infield and ALP compared with patients receiving SBRT alone, suggesting that piecemeal separation surgery does not locally spread tumor cells, leading to an increased risk of ALP failure, and supporting the use of conformal postoperative S-SBRT.
Authors
- Mark M. Zaki (ORCID: https://orcid.org/0000-0002-5155-042X)
- Varun Kathawate
- Rushikesh S. Joshi (ORCID: https://orcid.org/0000-0001-5251-5856)
- Yamaan S. Saadeh (ORCID: https://orcid.org/0000-0001-6269-4392)
- Robert Y. North (ORCID: https://orcid.org/0000-0001-6757-5595)
- Peyton Goethe (ORCID: https://orcid.org/0000-0003-3008-3196)
- Lila Tudrick (ORCID: https://orcid.org/0009-0005-6148-2255)
- Whitney E. Muhlestein (ORCID: https://orcid.org/0000-0003-2801-2081)
- Joseph R. Linzey (ORCID: https://orcid.org/0000-0002-2849-5012)
- Oludotun Ogunsola
- Ayobami Ward (ORCID: https://orcid.org/0009-0008-6616-7694)
- Joseph R. Evans (ORCID: https://orcid.org/0000-0002-1342-270X)
- Nicholas J. Szerlip (ORCID: https://orcid.org/0000-0003-1116-3422)
- Johan Lee (ORCID: https://orcid.org/0009-0002-1286-5354)
- Will Jackson (ORCID: https://orcid.org/0000-0001-8709-5978)
- Michael J. Strong (ORCID: https://orcid.org/0000-0003-1988-6262)
- Noah Willet
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- University of Michigan (US)
Publication Details
- Journal
- American Journal of Clinical Oncology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1097/coc.0000000000001164
- Citations
- 5
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 10.03