Exploring PANoptosis Related Novel Diagnostic Biomarkers and Potential Drugs for Sarcopenia based on Machine Learning and Experimental Validation
In this study, the hub genes <i>LTBP2, ETS2</i>, and <i>H3.3B</i> associated with PANoptosis in sarcopenia were successfully identified through a combination of bioinformatics and experimental verification methods. This establishes a foundation for new candidate diagnostic and therapeutic targets for sarcopenia.
Authors
- Chao Song (ORCID: https://orcid.org/0000-0002-0828-3426)
- Linhai Yang
- Jun Luo (ORCID: https://orcid.org/0000-0001-7120-5618)
- Hanhao Dai (ORCID: https://orcid.org/0000-0002-8197-3183)
- Zhibo Deng
- Rongsheng Zhang
- Yu Xiu
- Jie Yu (ORCID: https://orcid.org/0009-0005-5228-3297)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
- Fuzhou University (CN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-01-22
- DOI
- https://doi.org/10.2174/0109298673341863241210112605
- Citations
- 1
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.67