Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer
The ERG-based risk model effectively predicts the prognosis of BRCA patients and shows a strong link with the immune microenvironment. IL33 stands out as a significant prognostic marker, crucial in the onset and advancement of BRCA. This highlights the necessity for additional studies and indicates that IL33 might be a potential target for BRCA treatment.
Authors
- He Xiao
- Zhun Zhang (ORCID: https://orcid.org/0009-0001-8218-5277)
- Mengjie Tang (ORCID: https://orcid.org/0000-0001-6701-2581)
- Lanhui Chen (ORCID: https://orcid.org/0009-0009-5643-2041)
- Xi Cheng (ORCID: https://orcid.org/0009-0001-2190-4397)
- Changjun Xie
Institutions
- Central South University (CN)
- Hunan Cancer Hospital (CN)
- Third Xiangya Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fphar.2025.1533571
- Citations
- 3
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- National Natural Science Foundation of China