Predicted indirectly recognizable HLA epitopes scores and clinical outcomes after haploidentical stem cell transplantation in pediatric patients with relapsed neuroblastoma
In conclusion, higher PIRCHE-I and PIRCHE-II scores are linked to better survival outcomes and reduced complications in pediatric haplo-SCT neuroblastoma patients. Incorporating PIRCHE scores into donor selection is expected to optimize transplant outcomes.
Authors
- Won Young Heo (ORCID: https://orcid.org/0000-0003-2695-9634)
- Eun Seop Seo (ORCID: https://orcid.org/0000-0002-8108-5311)
- Hee Won Cho (ORCID: https://orcid.org/0000-0002-0440-645X)
- Hee Young Ju (ORCID: https://orcid.org/0000-0001-6744-0412)
- Ki Woong Sung (ORCID: https://orcid.org/0000-0001-5989-4772)
- In Hwa Jeong (ORCID: https://orcid.org/0000-0001-8383-8228)
- Keon Hee Yoo (ORCID: https://orcid.org/0000-0002-5980-7912)
- Eun‐Suk Kang (ORCID: https://orcid.org/0000-0001-6386-6520)
- Ji Won Lee (ORCID: https://orcid.org/0000-0003-0084-1304)
- Ju Kyung Hyun (ORCID: https://orcid.org/0000-0001-9371-3808)
Institutions
- Samsung (South Korea) (KR)
- Dong-A University Hospital (KR)
- Samsung Medical Center (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1517387
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Samsung