Electrical stimulation of the sciatic nerve restores inspiratory diaphragm function in mice after spinal cord injury
Our findings indicate that therapies targeting limb afferents could potentially be used to improve breathing in patients with cervical spinal cord injury and provide an experimental model to further investigate the neural pathways by which limb afferents can increase respiratory muscle activity.
Authors
- Sarah Baumgartner
- Mitesh Patel (ORCID: https://orcid.org/0000-0002-3594-5448)
- Ian Walling (ORCID: https://orcid.org/0000-0002-2150-2806)
- Steven A. Crone (ORCID: https://orcid.org/0000-0001-9644-2767)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Frontiers in Neural Circuits
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fncir.2024.1480291
- Citations
- 4
- Primary Topic
- Neuroscience of respiration and sleep
- Type
- article
- Field-Weighted Citation Impact
- 3.66
Funders
- Craig H. Neilsen Foundation
- Cincinnati Children's Hospital Medical Center