Perioperative Chemotherapy or Preoperative Chemoradiotherapy in Esophageal Cancer
Perioperative chemotherapy with FLOT led to improved survival among patients with resectable esophageal adenocarcinoma as compared with preoperative chemoradiotherapy. (Funded by the German Research Foundation; ESOPEC ClinicalTrials.gov number, NCT02509286.).
Authors
- Tobias Keck (ORCID: https://orcid.org/0000-0001-7651-6183)
- Andreas Pascher (ORCID: https://orcid.org/0000-0002-0801-1949)
- Michael Ghadimi (ORCID: https://orcid.org/0000-0001-8208-1526)
- Thea G. A. Strieder
- Gerald Illerhaus (ORCID: https://orcid.org/0000-0002-0009-8138)
- Simone Zimmermann
- Christian Krautz (ORCID: https://orcid.org/0000-0002-2537-5824)
- S Daum (ORCID: https://orcid.org/0000-0003-0060-6013)
- Johan Friso Lock (ORCID: https://orcid.org/0000-0002-9007-3937)
- Gunnar Folprecht (ORCID: https://orcid.org/0000-0002-9321-9911)
- Frank Benedix
- Peter Grimminger (ORCID: https://orcid.org/0000-0002-1859-9213)
- Thomas Brunner (ORCID: https://orcid.org/0000-0002-1594-4712)
- Stefan Utzolino (ORCID: https://orcid.org/0000-0003-1802-0985)
- Jens Hoeppner (ORCID: https://orcid.org/0000-0002-3485-7446)
- Birte Kulemann (ORCID: https://orcid.org/0000-0003-0278-7874)
- Jakob R. Izbicki (ORCID: https://orcid.org/0000-0001-6807-8224)
- Rolf Mahlberg
- Christiane J. Bruns (ORCID: https://orcid.org/0000-0001-6590-8181)
- Florian Lordick (ORCID: https://orcid.org/0000-0001-8591-9339)
- Jens Werner (ORCID: https://orcid.org/0000-0001-7813-2482)
- Rainer Claus (ORCID: https://orcid.org/0000-0003-2617-8766)
- Ines Gockel (ORCID: https://orcid.org/0000-0001-7423-713X)
- Peter Bronsert (ORCID: https://orcid.org/0000-0001-8558-0347)
- Claudia Schmoor (ORCID: https://orcid.org/0000-0001-5610-9425)
- Peter Thuss‐Patience (ORCID: https://orcid.org/0000-0002-8544-9872)
- Maximilian Schmeding (ORCID: https://orcid.org/0000-0002-8547-287X)
- Ernst Reitsamer
- Ulf P. Neumann (ORCID: https://orcid.org/0000-0002-3831-8917)
- Berthold Gerdes (ORCID: https://orcid.org/0000-0002-8661-6986)
- Benedikt Reichert
- Detlef Imhof
Institutions
- Universität Hamburg (DE)
- University Medical Center Freiburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1056/nejmoa2409408
- Citations
- 183
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 365.17
Funders
- Deutsche Forschungsgemeinschaft