Immune regulatory genes impact the hot/cold tumor microenvironment, affecting cancer treatment and patient outcomes
In this study, we developed a framework for discerning clinically significant immune subtypes across various cancer types, further identifying several potential targets for converting cold tumors into hot tumors to enhance anticancer treatment efficacy.
Authors
- Gu Tang
- Xiaorong Zhou (ORCID: https://orcid.org/0000-0002-6120-7318)
- Xiaoling Ding
- Mengmeng Sang (ORCID: https://orcid.org/0000-0001-5249-002X)
- Qiwen Wang (ORCID: https://orcid.org/0000-0002-4255-3960)
- Liming Mao (ORCID: https://orcid.org/0000-0002-9740-820X)
- Jia Ge (ORCID: https://orcid.org/0000-0002-5986-3076)
- Juan Ge
- Jiarun Wu
Institutions
- Shanghai University (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fimmu.2024.1382842
- Citations
- 6
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.78
Funders
- National Natural Science Foundation of China