Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis
PAE could alleviate colon inflammation and mucosal barrier damage in UC, which are related to the inhibition of Notch1 and the regulation of the Th17/Treg balance. PAE might be a potential candidate agent for UC treatment.
Authors
- Muyuan Chen (ORCID: https://orcid.org/0000-0003-1311-7868)
- Shiyin Liu
- Huibiao Li (ORCID: https://orcid.org/0000-0002-5557-6870)
- Yanqiu Zheng (ORCID: https://orcid.org/0000-0003-2356-5031)
- Xinlin Chen (ORCID: https://orcid.org/0000-0002-0584-9391)
- Yanwu Li (ORCID: https://orcid.org/0000-0002-8794-659X)
- Jinbin Song
- Fan Xiao
- Shiyu Qi
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.3389/fphar.2024.1534772
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Natural Science Foundation of China