Electrophysiological properties of melanin-concentrating hormone neuron subpopulations defined by anatomical localization and CART expression

Our results suggest that MCH/CART- cells are electrophysiologically distinct, whereas MCH/CART+ cells are largely similar despite their diffuse distribution in the hypothalamus. It is therefore a combination of intrinsic electrophysiological properties and neurochemical identities, in addition to anatomy and connectivity that are likely to be critical in defining functional subpopulations of MCH neurons.

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Publication Details

Journal
Frontiers in Cellular Neuroscience
Published
2025-01-22
DOI
https://doi.org/10.3389/fncel.2024.1439752
Primary Topic
Regulation of Appetite and Obesity
Type
article
Field-Weighted Citation Impact
0.00

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article

Electrophysiological properties of melanin-concentrating hormone neuron subpopulations defined by anatomical localization and CART expression

Michiru Hirasawa, Lisa Z. Fang, M. CHOWDHURY, Rafiat Damilola Adekunle
Frontiers in Cellular Neuroscience
Regulation of Appetite and Obesity
article

Electrophysiological properties of melanin-concentrating hormone neuron subpopulations defined by anatomical localization and CART expression

Michiru Hirasawa, Lisa Z. Fang, M. CHOWDHURY, Rafiat Damilola Adekunle
article en

Abstract

Our results suggest that MCH/CART- cells are electrophysiologically distinct, whereas MCH/CART+ cells are largely similar despite their diffuse distribution in the hypothalamus. It is therefore a combination of intrinsic electrophysiological properties and neurochemical identities, in addition to anatomy and connectivity that are likely to be critical in defining functional subpopulations of MCH neurons.

Frontiers in Cellular NeuroscienceVol. 18
Memorial University of Newfoundland (CA)
Canadian Institutes of Health Research
Good health and well-being
Openalex Percentile: Top 98%
Regulation of Appetite and Obesity
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