Immunogenicity of an in-silico designed multi-epitope DNA vaccine encoding ROP21 and ROP29 of Toxoplasma gondii against both acute and chronic toxoplasmosis in BALB/c mice
We found that multiepitope protein vaccination could provide more protective immunity against chronic and acute toxoplasmosis infection compared to control.
Authors
- Fatemeh Ghaffarifar (ORCID: https://orcid.org/0000-0003-0891-8214)
- Amir KarimiPourSaryazdi
- Masoud Foroutan (ORCID: https://orcid.org/0000-0002-8661-7217)
- John Horton (ORCID: https://orcid.org/0000-0001-7047-5106)
- Abdolhossein Dalimi (ORCID: https://orcid.org/0000-0001-5591-5513)
- Javid Sadraei (ORCID: https://orcid.org/0000-0003-3312-765X)
Institutions
- Hamedan University of Medical Sciences (IR)
- Tarbiat Modares University (IR)
- Animal Free Research UK (GB)
Publication Details
- Journal
- Microbial Pathogenesis
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1016/j.micpath.2025.107321
- Citations
- 6
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 12.29