Association of <scp> <i>GLP1R</i> </scp> locus with mental ill‐health endophenotypes and cardiometabolic traits: A trans‐ancestry study in <scp>UK</scp> Biobank
GLP1R variants have consistent cardiometabolic effects across ancestries, but effects on MIH phenotypes are more varied. Any observed behavioural changes with GLP1RA are likely not acting directly through GLP1R.
Authors
- Joey Ward (ORCID: https://orcid.org/0000-0003-0951-8511)
- Paul I. Welsh (ORCID: https://orcid.org/0000-0002-7970-3643)
- Jana Anderson (ORCID: https://orcid.org/0000-0001-7290-6635)
- Waneisha Jones (ORCID: https://orcid.org/0000-0002-6501-3668)
- Jill P. Pell (ORCID: https://orcid.org/0000-0002-8898-7035)
- Madeleine M. E. Hayman
- Donald M. Lyall (ORCID: https://orcid.org/0000-0003-3850-1487)
- Rona J. Strawbridge (ORCID: https://orcid.org/0000-0001-8506-3585)
- Alisha Aman (ORCID: https://orcid.org/0000-0003-4022-5880)
- Naveed A. Sattar (ORCID: https://orcid.org/0000-0002-1604-2593)
Institutions
- Karolinska Institutet (SE)
- University of Glasgow (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1111/dom.16178
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Wellcome Trust
- Scottish Government
- British Heart Foundation
- Northwest Regional Development Agency
- Medical Research Council