ENDOGENOUS INTOXICATION INDICATORS LABORATORY EVALUATION IN THE MILK OF COWS

The purpose of research is to study the indicators of endogenous intoxication in cows' milk. Tasks: to form a sample of apparently healthy lactating cows and take milk and blood samples from them; determine the range of concentrations of MMM in cows' milk; in a comparative aspect to study the indicators of EI in different biological fluids. The study was carried out in the conditions of the livestock farm of the Krasnodar Region on Holsteinized cows that are in the period of milking. A sample of 100 conditionally healthy cows was formed, ranked by age, body weight and physiological state. The level of endogenous intoxication in the body of cows was studied by three fractions of MMM in blood and milk at wavelengths – λ = 238 nm (MMM 238), λ = 254 nm (MMM 254) and λ = 280 nm (MMM 280). A range of indicators of endogenous intoxication in cows' milk was obtained, with the highest level being the nuclear fraction – MMM 238 when registering values in the range from 1.051 to 1.452 arb. units. The minimum content was registered in the MMM 254 fraction, the parameters of which varied in the range from 0.345 to 0.568 arb. units. The concentration of MMM in the blood has a pronounced positive correlation with its level in milk, while the strongest relationship was established for the MMM 254 fraction. veterinary medicine and clinical biochemistry non-invasive research methods.