Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA

This study is the first to use bioinformatics methods to identify ZDHHC22 as a key KPRG in AD, highlighting its potential role in disease diagnosis and immune regulation. The regulatory network of ZDHHC22 provides new insights into the molecular mechanisms of AD and lays the foundation for future targeted therapeutic strategies.

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Publication Details

Journal
European journal of medical research
Published
2025-01-22
DOI
https://doi.org/10.1186/s40001-025-02277-0
Citations
3
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
3.49
Controls
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article

Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA

Xiyao Zhao, Sanying Mao, Yilong Man, Lei Wang et al.
3 citations
European journal of medical research
Alzheimer's disease research and treatments
3.49
article

Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA

Xiyao Zhao, Sanying Mao, Yilong Man, Lei Wang, Kaiyuan Li
article en
3 citations

Abstract

This study is the first to use bioinformatics methods to identify ZDHHC22 as a key KPRG in AD, highlighting its potential role in disease diagnosis and immune regulation. The regulatory network of ZDHHC22 provides new insights into the molecular mechanisms of AD and lays the foundation for future targeted therapeutic strategies.

European journal of medical researchVol. 30(1)
Dalian Medical University (CN), The First People's Hospital of Changde (CN), Shandong First Medical University (CN)
Zero hunger
Openalex Percentile: Top 9%
Alzheimer's disease research and treatments
3.49
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