SS-31@Fer-1 Alleviates ferroptosis in hypoxia/reoxygenation cardiomyocytes via mitochondrial targeting
SS-31@Fer-1 effectively suppressed ferroptosis in H/R-induced cardiomyocytes by maintaining cellular iron homeostasis, improving mitochondrial function, and inhibiting oxidative stress. These findings provide novel insights and opportunities for alleviating myocardial I/R injury.
Authors
- Qizheng Lu
- Hao Zheng (ORCID: https://orcid.org/0000-0002-2821-4153)
- Jinbo Ou
- Hui Han (ORCID: https://orcid.org/0000-0002-5644-9187)
- Yunli Shen (ORCID: https://orcid.org/0000-0002-3204-6594)
Institutions
- Fudan University (CN)
- Zhongshan Hospital (CN)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1016/j.biopha.2025.117832
- Citations
- 16
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 24.29