Intervention With Concentrated Albumin for Undifferentiated Sepsis in the Emergency Department (ICARUS-ED): A Pilot Randomized Controlled Trial
Early identification, trial enrollment, and intervention in ED patients with sepsis is feasible. In this pilot study, concentrated albumin given early in resuscitation did not improve SBP at 24 hours. Albumin was associated with less total fluid and vasopressor requirements and improved organ dysfunction. A multicenter study is indicated.
Authors
- Mercedes Ray
- Angela Hills (ORCID: https://orcid.org/0000-0002-9832-0461)
- Jaimi Greenslade (ORCID: https://orcid.org/0000-0002-6970-5573)
- Julian Williams (ORCID: https://orcid.org/0000-0002-8366-7307)
Institutions
- Royal Brisbane and Women's Hospital (AU)
Publication Details
- Journal
- Annals of Emergency Medicine
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1016/j.annemergmed.2024.12.016
- Citations
- 7
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.48
Funders
- Emergency Medicine Foundation