Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining
KRT16 and ANXA10 are potential genes regulating the development of LUAD. Also, they may be potential targets for the targeted therapy of LUAD by inhibiting the proliferation of lung cancer cells and blocking the cell cycle by affecting key protein expression levels at cell cycle checkpoints.
Authors
- Wenjian Liu (ORCID: https://orcid.org/0000-0002-1630-3466)
- Jianzhong Shen (ORCID: https://orcid.org/0000-0002-8502-8445)
- Xiao-Yun Fan (ORCID: https://orcid.org/0000-0002-5852-1496)
- Renquan Zhang (ORCID: https://orcid.org/0009-0001-5840-3529)
Institutions
- Anhui Medical University (CN)
- PLA Electronic Engineering Institute (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1007/s12672-024-01707-5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00