Spatiotemporal analysis of Plasmodium falciparum erythrocyte binding antigen-175 gene dimorphism in Ghana
The F-allele was the most prevalent form across all age groups, followed by the C allele and mixed F/C alleles. No significant difference in allele prevalence was observed between the high malaria season (wet) and low malaria season (dry). However, a statistically significant difference in the temporal prevalence of pure alleles (F & C) between two time points was observed. The current study adds to the existing body of knowledge on eba-175 allelic dimorphism and highlights the co-circulation of alleles in high malaria endemic areas in Ghana.
Authors
- Victor E. Kornu
- Charles Mensah (ORCID: https://orcid.org/0000-0002-2292-0591)
- Collins M. Morang’a (ORCID: https://orcid.org/0000-0002-6988-150X)
- Gordon A. Awandare (ORCID: https://orcid.org/0000-0002-8793-3641)
- Eric S. Donkor (ORCID: https://orcid.org/0000-0002-9368-0636)
- Francis Dzabeng (ORCID: https://orcid.org/0000-0001-7097-4968)
- Owais Ahmed (ORCID: https://orcid.org/0000-0003-0786-3290)
- Yaw Aniweh (ORCID: https://orcid.org/0000-0002-8415-2727)
- Adetola A. Kassim (ORCID: https://orcid.org/0000-0002-0484-5903)
- Lucas Amenga–Etego (ORCID: https://orcid.org/0000-0003-4468-0506)
- Samirah Saiid (ORCID: https://orcid.org/0009-0008-0778-6276)
- Michael Essien Sakyi
- Abraham Y. Kpirikai
- Albert Yao Kudakpo
- Belinda Ofosu
- Josie N. A. Okai
- Frederica Malm
Institutions
- University of Ghana (GH)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12936-025-05263-3
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation
- National Institute for Health and Care Research