Effects of Shenfu Decoction on Neutrophil Chemotactic Function in Septic Mice
Sepsis involves a complex cascade of inflammatory reactions and immune system dysregulation. Neutrophils play a crucial role in modulating the anti-inflammatory response, which is vital for managing sepsis. Impaired chemotaxis of granulocytes can significantly impact the outcome of sepsis. Shenfu Decoction, by tonifying Qi and warming Yang, enhances the propelling function of Qi for promoting the chemotactic function of neutrophils. This study aimed to investigate the effects of Shenfu Decoction on the chemotactic function of neutrophils in septic mice and the underlying mechanisms.
Authors
- Xiaolong Xu (ORCID: https://orcid.org/0000-0003-3333-0906)
- Xucheng Li (ORCID: https://orcid.org/0000-0002-8081-2708)
- Yi Jiang (ORCID: https://orcid.org/0000-0002-6802-5189)
- Qingquan Liu (ORCID: https://orcid.org/0000-0003-0828-0361)
- Li W (ORCID: https://orcid.org/0000-0003-1792-5336)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-3197-0427)
- Kangli Wang (ORCID: https://orcid.org/0000-0002-6987-2558)
- Rui Zhu (ORCID: https://orcid.org/0000-0002-5985-1235)
- Chenxi Wang (ORCID: https://orcid.org/0009-0003-1457-5120)
Publication Details
- Journal
- Future Integrative Medicine
- Published
- 2025-01-22
- DOI
- https://doi.org/10.14218/fim.2024.00040
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- Natural Science Foundation of Hubei Province