Early Cold-stored Platelet Transfusion following Traumatic Brain Injury
In brain-injured patients requiring platelet transfusion, early CSP transfusion is feasible and did not result in improved 6-month Glasgow Coma Scale-extended scores. Early CSP transfusion was associated with a lower rate of neurosurgical operative intervention without an increase in adverse events. The storage age of the CSP product was not associated with outcome differences. Future phase 3 clinical trials are required to determine clinical outcome differences and safety attributable to CSP transfusion after TBI.
Authors
- Mark H. Yazer (ORCID: https://orcid.org/0000-0001-6740-2758)
- Philip Charles Spinella (ORCID: https://orcid.org/0000-0003-1721-0541)
- Matthew D. Neal (ORCID: https://orcid.org/0000-0001-8931-6236)
- Christine M. Leeper (ORCID: https://orcid.org/0000-0002-8561-8760)
- Francis Xavier Guyette (ORCID: https://orcid.org/0000-0002-9151-4896)
- Raquel M. Forsythe (ORCID: https://orcid.org/0000-0002-9810-9930)
- Ava M. Puccio (ORCID: https://orcid.org/0000-0003-2569-9607)
- Stephen R. Wisniewski (ORCID: https://orcid.org/0000-0002-3877-9860)
- Joshua B. Brown (ORCID: https://orcid.org/0000-0002-6936-035X)
- James F. Luther (ORCID: https://orcid.org/0000-0001-6118-5318)
- Allison G. Agnone
- Laura Vincent (ORCID: https://orcid.org/0000-0003-0168-4734)
- Ashley M. Harner
- Jason L. Sperry
- Emily T. Love
- David O. Okonkwo
- Donovan P. Brubaker
Institutions
- University of Pittsburgh (US)
- Ta Solutions (China) (CN)
- Neurological Surgery (US)
Publication Details
- Journal
- Annals of Surgery
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1097/sla.0000000000006640
- Citations
- 18
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 13.94