Autoimmune polyglandular syndrome type 1 in children: A clinical case
The autoimmune polyglandular syndrome is a rare autoimmune disease characterized by simultaneous primary involvement of the endocrine glands and other organs. It is caused by a defect in the AutoImmune REgulator (AIRE) gene. The paper presents data on autoimmune polyglandular syndrome type 1, including the frequency of its occurrence, features of the clinical presentation, course, and prognosis. In the described clinical case, we present patient management with this syndrome, features of the disease course, the challenges of diagnosis and therapy choice, and the need for follow-up observation.
Authors
- E. R. Radchenko (ORCID: https://orcid.org/0000-0001-5717-7171)
- Goar Okminyan (ORCID: https://orcid.org/0000-0002-1578-5870)
- И. Н. Захарова (ORCID: https://orcid.org/0000-0003-4200-4598)
- I. D. Maykova (ORCID: https://orcid.org/0000-0003-2700-2607)
- И. Н. Холодова (ORCID: https://orcid.org/0000-0003-0090-6980)
- Elena P. Kulagina
- И. М. Османов (ORCID: https://orcid.org/0000-0003-3181-9601)
- Е. В. Москалева (ORCID: https://orcid.org/0000-0003-4196-0713)
- Yu. А. Dmitrieva (ORCID: https://orcid.org/0000-0003-0668-7336)
- A. S. Vorobyova
Institutions
- Pirogov Russian National Research Medical University (RU)
- Russian Medical Academy of Continuous Professional Education (RU)
- TRC Companies (United States) (US)
- Children's City Clinical Hospital №11 (RU)
Publication Details
- Journal
- Pediatrics Consilium Medicum
- Published
- 2024-12-15
- DOI
- https://doi.org/10.26442/26586630.2024.4.203061
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00