Towards routine high-throughput analysis of fecal bile acids: validation of an enzymatic cycling method for the quantification of total bile acids in human stool samples on fully automated clinical chemistry analyzers
The advantages of enzymatic TBA analysis on fully automated clinical chemistry platforms can be exploited for the routine analysis of stool samples. However, cycling assays may benefit from reference standards that take into account the composition of the fecal BA pool.
Authors
- Tobias Frömel (ORCID: https://orcid.org/0000-0003-4812-0127)
- Kai Prager
- Matthias Grimmler (ORCID: https://orcid.org/0000-0003-2860-3391)
- Christoph Peter (ORCID: https://orcid.org/0000-0002-0048-2279)
- Tina Leber
- Angelique Masetto
Institutions
- Hochschule Fresenius (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1515/cclm-2024-1414
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00