Serum ALT activity and its isoenzymes as potential biomarkers for diagnosis of Sarcopenia in older adults: a retrospective, cross-sectional study
In older adults, a low serum ALT activity level was an independent risk factor for low ASMI, HGS, physical performance, and sarcopenia. The serum ALT1/ALT2 ratio emerged as an independent risk factor for low physical performance and sarcopenia. The new indices, Logit_P1 and Logit_P2, demonstrated diagnostic value for sarcopenia.
Authors
- Hui Sheng (ORCID: https://orcid.org/0000-0003-1430-3224)
- Yujie Jing
- Shen Qu (ORCID: https://orcid.org/0000-0003-0811-7070)
- Jiaying Ge
- Ran Cui
- Siqi Sun
- Jiangping Zeng
- Huihui Ma
- Chunhua Qian
- Nannan Li (ORCID: https://orcid.org/0000-0001-7799-0880)
Institutions
- Tongji University (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1186/s12877-025-05697-z
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality