Residual pain and fatigue are affected by disease perception in rheumatoid arthritis in sustained clinical and ultrasound remission
Moreover,73% satisfied female Rem/Ra patients presented an acceptable pain compared to 23% unsatisfied female Rem/RA patients (p = 0.001). RP in RA patients in remission can represent the way by which the patients communicate their state of non-acceptance of the disease. It can be useful to treat RP with the appropriate treatments. Key Points • Rheumatoid arthritis patients still reported unacceptable residual pain despite sustained clinical and ultrasound remission and despite the low grade/absence of histological synovitis. • Only a small rate of rheumatoid arthritis patients in sustained clinical and ultrasound remission showed residual pain as part of a central sensitivity syndrome or psychiatric disorders. • Rheumatoid arthritis patients in sustained clinical and ultrasound remission complained residual pain and fatigue as part of not acceptance of disease and/or dissatisfaction in the disease management.
Authors
- Stefano Alivernini (ORCID: https://orcid.org/0000-0002-7383-4212)
- Dario Bruno (ORCID: https://orcid.org/0000-0002-6647-9208)
- Clara Di Mario (ORCID: https://orcid.org/0000-0001-9459-3326)
- Barbara Tolusso (ORCID: https://orcid.org/0000-0002-9108-6609)
- Simone Perniola (ORCID: https://orcid.org/0000-0001-6918-4731)
- Marco Gessi (ORCID: https://orcid.org/0000-0002-0461-1445)
- Luca Petricca (ORCID: https://orcid.org/0000-0003-3544-3162)
- Elisa Gremese (ORCID: https://orcid.org/0000-0002-2248-1058)
- Martina Calabretta
- Denise Campobasso
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Verona (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Clinical Rheumatology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.1007/s10067-025-07331-0
- Citations
- 3
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 5.00
Funders
- Ministero della Salute
- Università Cattolica del Sacro Cuore