Mechanism of Wuling powder modulating proBDNF/p75NTR/sortilin and BDNF/TrkB pathways in the treatment of ulcerative colitis complicated with depression
This study confirmed that Wuling powder may play an antidepressant role by regulating the balance of the proBDNF/p75NTR/sortilin and BDNF/TrkB signalling pathways and further relieve intestinal inflammation in UC.
Authors
- Rong Huang (ORCID: https://orcid.org/0000-0002-7850-6736)
- Wan-Ting Cao
- Xinyi Yao (ORCID: https://orcid.org/0000-0002-7371-0885)
- Jingjing Wang (ORCID: https://orcid.org/0000-0003-3170-8952)
- Menglin Li (ORCID: https://orcid.org/0000-0001-8639-5899)
- Yihong Fan (ORCID: https://orcid.org/0000-0001-9554-0541)
Institutions
- Zhejiang Chinese Medical University (CN)
- Jinhua Academy of Agricultural Sciences (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- First Hospital of Jiaxing (CN)
- Third People's Hospital of Huzhou (CN)
- Jinhua Central Hospital (CN)
- Yueqing People's Hospital (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-01-23
- DOI
- https://doi.org/10.3748/wjg.v31.i8.100227
- Citations
- 3
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 3.34