Genetically mimicked effects of evinacumab on psoriasis: a drug target Mendelian randomization study.
The genetically mimicked effect of evinacumab has the potential to reduce the risk of psoriasis and arthropathic psoriasis by lowering circulating triglyceride and LDL-C concentrations, respectively. These findings suggest that evinacumab may help prevent psoriasis and psoriatic arthritis progression in clinical practice.
Authors
- Zhenhuang Zhuang (ORCID: https://orcid.org/0000-0001-9150-3081)
- Wendi Xiao
- Siyan Zhan (ORCID: https://orcid.org/0000-0001-7252-5349)
- Mingyue Wang (ORCID: https://orcid.org/0000-0001-8317-3414)
- Ruoyu Li (ORCID: https://orcid.org/0000-0003-1451-3598)
- Zhihui Yang (ORCID: https://orcid.org/0000-0003-1193-6894)
- Tao Huang (ORCID: https://orcid.org/0000-0001-5206-2471)
- Yan Wu (ORCID: https://orcid.org/0000-0002-9896-8460)
Institutions
- Peking University (CN)
- Beijing Academy of Artificial Intelligence (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-02-01
- DOI
- https://doi.org/10.6133/apjcn.202502_34(1).0004
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00