The effectiveness of early use of a probiotic drug in calf rearing

The aim of the research was to evaluate the effect of a probiotic drug on metabolic parameters, the microbiome of the digestive tract and the dynamics of body weight gain in calves. To do this, newborn young (n=10) with the first colostrum drink (hereinafter with milk) once a day for two weeks were given 0.5 ml of a probiotic drug containing 10 7 CFU /ml of Lactobacillus plantarum PL-99, Lactobacillus buchneri BX-99 and Bacillus subtilis BS2017 in a ratio of 1:1:1. The control was animals that had not been given a probiotic drug (n=10). It was shown that against the background of the use of bacterial culture, the content of total protein in blood serum was 10,0% (P<0,05) higher than that of the control group, globulins by 24,8% (P<0,05) alkaline phosphatase activity by 48,8% (P<0,05). The use of probiotics was accompanied by an increase in the total bacterial mass in the intestinal contents (by 1×10 8,44 ; P≤0,01), including the number of lactobacilli (by 1×10 6,79 ; P≤0,05), bacteria of the genera Staphylococcus (by 1×10 2,97 ; P≤0,01), Fusobacterium (by 1×10 7,52 ; P≤0,05), Clostridium (by 1×10 8,07 ; P≤0,001), Corynebacterium (by 1×10 5,02 ; P≤0,01). At the same time, the concentration of microorganisms such as Streptococcus spp , Eubacterium spp , Peptostreptococcus spp , which can cause diseases of the digestive tract, significantly decreased. The use of the biopreparation contributed to a 40% reduction in the occurrence of diarrhea in young animals and an increase in the average daily increase in the first month of cultivation by 36,7 g (P <0,05). Thus, early administration of the probiotic under study during the first two weeks of the neonatal period has a beneficial effect on nitrogen metabolism, the formation of intestinal microbiocenosis and the intensity of body weight gain, as well as a decrease in the incidence of diarrhea in calves.