The effectiveness of using progestamag® to optimize reproductive function in cows and heifers

The aim of the research was to evaluate the effectiveness of the use of various doses of Progestamag® included in the "CoSynch" scheme, as well as in the treatment of ovarian hypofunction. The experimental work was performed in the conditions of the Komi Republic on Ayrshire breed animals. Cows and heifers exhibiting sexual cyclicity with yellow bodies present on the ovaries were selected for synchronization. The efficacy of Progestamag® in the "Co-Synch" scheme was studied in heifers at dosages of 1 and 2 ml, and in cows of 1, 2 and 4 ml. The effectiveness of the drug in correcting gonadal hypofunction was evaluated in lactating cows by intramuscular administration of the drug in doses of 5 and 10 ml. It was found that the maximum fertilization after the first insemination was observed in heifers receiving 1 ml of progestin – 85.7%, whereas in the group without the use of a progesterone-containing drug and in the group where 2 ml of the drug was injected, the indicator was 45.7% lower. The frequency of insemination for pregnancy among heifers treated with the studied drug at a dose of 1 ml was 0.70 and 0.56 lower compared with the control (P≤0.001) and the second (P≤0.05) experimental group, respectively. In cows, against the background of the use of progesterone suspension in the "Co-Synch" scheme, the optimal result was established after the administration of 2 ml of progestin – the frequency of insemination for fertilization was lower by 0.25...1.35 compared with animals of other groups. With ovarian hypofunction, a dosage of 10 ml caused a comparable result obtained against the background of treatment with 2.5% progesterone solution, and the optimal therapeutic effect was revealed in a group of animals receiving 5 ml of the drug. The indicated dosage was characterized by a 0.50...0.69 lower insemination index and a 2.3...2.5 times shorter infertility period (P≤0.05).