The role of mucin in non-specific ulcerative colitis

The study of mucin in the mucosa in ulcerative colitis represents promising basic research that may help improve therapeutic outcomes. A comparative morphological study of the mucous membrane in chronic superficial colitis and ulcerative colitis was carried out in the work. It was noted that in ulcerative colitis there is a progressive atrophy of the columnar epithelium, crypts and goblet cells, a decrease in mucin secretion and a change in its characteristics with a predominance of alcian + mucopolysaccharides. It is possible that a violation of the secretion of mucus in the mucous membrane of the colon can lead to the development of dysregenerative and dysplastic processes, which requires further study.