The use of botulinum toxin in ophthalmology

Introduction: Botulinum toxin is an exotoxin produced by the anaerobic bacteria Clostridium botulinum. It is one of the most potent neurotoxins known and used in medicine. Its versatile use covers various fields of medicine, including ophthalmology. Aim: The purpose of this article is to discuss the current indications and potential uses of botulinum toxin in ophthalmology. State of the art brief: Botulinum toxin is widely used in ophthalmology for both therapeutic and aesthetic purposes. Thanks to its mechanism of action of inhibiting the release of acetylcholine, it leads to muscle paresis and inhibition of the function of the exocrine glands. This makes it effective in treating such conditions as, for example, strabismus, nystagmus, epiphora, and eyelid spasm. On the other hand, in aesthetic medicine it is used to reduce , "crow's feet". Conclusions: The properties of botulinum toxin make it a beneficial therapeutic tool used in ophthalmology. Studies show its effectiveness in treating various ocular muscle dysfunctions and excessive tearing.

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Publication Details

Journal
Prospects in Pharmaceutical Sciences
Published
2024-12-13
DOI
https://doi.org/10.56782/pps.253
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
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article

The use of botulinum toxin in ophthalmology

Mikołaj Borek, Katarzyna Łysiak, Paulina Przywara, Barbara Maziarz et al.
Prospects in Pharmaceutical Sciences
Botulinum Toxin and Related Neurological Disorders
article

The use of botulinum toxin in ophthalmology

Mikołaj Borek, Katarzyna Łysiak, Paulina Przywara, Barbara Maziarz, Kinga Ściurka, Anna Łysiak, Natalia Bogumiłło, Julia Ignacak
article en

Abstract

Introduction: Botulinum toxin is an exotoxin produced by the anaerobic bacteria Clostridium botulinum. It is one of the most potent neurotoxins known and used in medicine. Its versatile use covers various fields of medicine, including ophthalmology. Aim: The purpose of this article is to discuss the current indications and potential uses of botulinum toxin in ophthalmology. State of the art brief: Botulinum toxin is widely used in ophthalmology for both therapeutic and aesthetic purposes. Thanks to its mechanism of action of inhibiting the release of acetylcholine, it leads to muscle paresis and inhibition of the function of the exocrine glands. This makes it effective in treating such conditions as, for example, strabismus, nystagmus, epiphora, and eyelid spasm. On the other hand, in aesthetic medicine it is used to reduce , "crow's feet". Conclusions: The properties of botulinum toxin make it a beneficial therapeutic tool used in ophthalmology. Studies show its effectiveness in treating various ocular muscle dysfunctions and excessive tearing.

Prospects in Pharmaceutical SciencesVol. 22(4)
Medical University of Lublin (PL), Ogród Zoologiczny w Krakowie (PL), Lukasiewicz Research Network - Krakow Institute of Technology (PL), Postgraduate School of Molecular Medicine (PL), 1 Military Clinical Hospital with Outpatient Clinic (PL), Krakow Cardiovascular Research Institute (PL), Grochowski Hospital (PL), Szpital Uniwersytecki w Krakowie (PL)
Openalex Percentile: Top 61%
Botulinum Toxin and Related Neurological Disorders
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The use of botulinum toxin in ophthalmology — Mikołaj Borek, Katarzyna Łysiak, et al. · Prospects in Pharmaceutical Sciences (2024) | TGRS Research Map | TGRS