Local oral immunity and psycho-emotional state in military personnel with chronic gingivitis

Purpose. To analyse the changes in local immunity in the oral fluid of servicemen of the Armed Forces of Ukraine with chronic catarrhal gingivitis depending on their psycho-emotional state. Material and methods. The study of local oral immunity in oral fluid was conducted in 22 military patients of the Armed Forces of Ukraine with chronic catarrhal gingivitis (main group), in 11 patients of civilian specialties with chronic catarrhal gingivitis (comparison group), and in 16 dentally healthy individuals (control group). Additionally, military patients in the main group were divided into 4 subgroups depending on their psychoemotional state. The determination of sIgA in the oral fluid was performed by the method of Mancini et al. The photoelectrocolorimetric method was used to measure lysozyme activity in the oral fluids of patients. The content of cortisol in the oral fluid of patients in the study groups was determined by a competitive enzyme-linked immunosorbent assay. Results. As a result of the laboratory studies, it was found that in patients with chronic catarrhal gingivitis, military personnel of the Armed Forces of Ukraine had a 1.2-fold decrease in the content of sIgA in the oral fluid (p<0.01) and lysozyme activity (p<0.05), against the background of an increase in cortisol levels by 61.18 % (p<0.01) compared to the data in the comparison group. Conclusion. Thus, summing up the data of laboratory studies, it can be stated that patients of the main group (military personnel of the Armed Forces of Ukraine) with chronic catarrhal gingivitis have a more pronounced weakening of local oral immunity, which is manifested by a decrease in sIgA levels and lysozyme activity, compared with similar data in the comparison group (patients of civilian professions) with chronic catarrhal gingivitis. At the same time, the imbalance of immunological parameters deepened with the deterioration of the psychoemotional state of patients in the main group, which was confirmed by an increase in the level of cortisol in the oral fluid.