CO-OCCURRENCE OF OROFACIAL CLEFTS AND CONGENITAL HEART DEFECTS IN COMPLEXES OF CONGENITAL MALFORMATIONS

The results of an analysis of the combination of orofacial clefts and congenital heart defects in complex congenital malformations are presented. Among 91 newborns with multiple congenital malformations that included orofacial clefts, 45 % had heart defects, the most frequent being cardiac septal defects. Of the 77 fetuses aborted for unclassified complexes of malformations with orofacial clefts, heart defects had 37.7 %, the most common were complex heart defects. The frequency of malformations of other systems included in complexes of congenital malformations with orofacial clefts and heart defects was also analysed.