Antioxidant and thrombolytic activities of Crinum asiaticum L.

Crinum asiaticum L. is a toxic plant and can be grown as an ornamental plant in Bangladesh. The present study was designed to determine in vitro antioxidant and thrombolytic activity of n-hexane, dichloromethane and ethyl acetate fractions of C. asiaticum. Antioxidant activity was determined by total phenolic content (TPC) analysis and DPPH radical scavenging assay method. The ethyl acetate fraction showed maximum antioxidant activity (IC50 = 35.44 μg/ml), may be due to the presence of highest amount of phenolic compounds (52.04 mg of GAE per gram of extractives) in this fraction. During thrombolytic assay, dichloromethane fraction of C. asiaticum (Conc.= 10 mg/ml) showed highest 32.59% clot lysis activity. The present study revealed that C. asiaticum possesses significant antioxidant and thrombolytic potential. Bangladesh J. Sci. Ind. Res. 59(4), 191-194, 2024