Spectral correlation of synthesized ethyl-4-(subs. phenyl)-6-methyl-2-oxo (or thio)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate
Urea or thiourea, ethyl acetoacetate, and substituted aromatic aldehydes were combined in a one-pot Biginelli coupling reaction to create a few 1, 2, 3, 4-tetrahydro pyrimidine-5-carboxylate derivatives without any unsafe organic solvent. The catalyst used for this reaction was nickel nitrate hexahydrate [Ni(NO3)2.6(H2O)]. The elemental analyses, mass spectral data, 1H-NMR, 13C-NMR, UV, and IR were used to characterize the separated pure products. Bangladesh J. Sci. Ind. Res. 59(4), 223-230, 2024
Authors
- S M Ahmed
- Uzzal Shaha
- Md. Habibur Rahman (ORCID: https://orcid.org/0000-0002-0137-3322)
- Muhammad Naeem Khan (ORCID: https://orcid.org/0000-0001-7123-9850)
- Md. Ershad Halim
- Kawsari Akhter
Institutions
- American International University-Bangladesh (BD)
- University of Dhaka (BD)
Publication Details
- Journal
- Bangladesh Journal of Scientific and Industrial Research
- Published
- 2024-12-30
- DOI
- https://doi.org/10.3329/bjsir.v59i4.75654
- Citations
- 1
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.25