AGENESIS OF CORPUS CALLOSUM. HEREDITARY FACTORS, PRENATAL DIAGNOSIS, CLINICAL MANIFESTATION

The corpus callosum (CC) is the largest commissure in the of the brain and plays a key role in the integration of information between the hemispheres. The most common malformation of the MT is agenesis (complete or partial). Estimated prevalence of 1:4,000-6,000 newborns. The clinical manifestations in patients vary over a wide spectrum: from asymptomatic course to severe neuropsychiatric disorders. The article presents data from 202 probands with CC agenesis who underwent medical and genetic counselling in Medical Centre «Mother and Child» from 2007 to 2022.