Radical surgical treatment methods for pancreatic tumors

Annotation. Pancreatic cancer is the leading cause of cancer-related mortality worldwide, ranking seventh among other neoplastic diseases with high mortality rates. The purpose of the work is to review and analyze the effectiveness of various surgical methods of pancreatic cancer treatment. Currently, the only radical treatment method for pancreatic cancer is surgical intervention. There is a range of surgical operations for pancreatic cancer, requiring the surgeon to differentiate and appropriately apply them to each clinical case. The choice of surgical treatment strategy primarily depends on assessing the resectability of the tumor, with the goal of achieving R0 resection and conducting lymphadenectomy. This article presents the results of an analysis of literature data and the outcomes of our own surgical experience over the past 15 years. It has been determined that among all radical surgical methods for treating pancreatic tumor lesions, segmental resections lead to significantly better overall patient condition with a lower percentage of complications and early mortality. Additionally, segmental resections allow for tumor removal while preserving the maximum volume of healthy parenchyma and maintaining normal anatomical and physiological conditions of the gastrointestinal tract. This substantially reduces the risk of pancreatic endocrine insufficiency, while maintaining a high quality of life and work capacity for patients. The main goal of treating pancreatic cancer is to improve and optimize radical surgical treatment methods while adhering to all oncological principles, reducing complication and mortality rates, and improving the rehabilitation period and overall patient condition.